Publication

selected publications

*: Equal contribution
†: Corresponding author

1. Chen F*, Wang X*, …, Vrieze S, Liu DJ. Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing. Nature Genetics. 2023 Jan 26:1-0. (link) (Media coverage: Penn State News, 澎湃新闻)
2. Saunders GRB*, Wang X*, Chen F*, …, Liu DJ, Vrieze S. Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature. 2022 Dec;612(7941):720-724. (link) (Selected media coverage: Penn State News, Daily Mail, New Scientist, GenomeWeb, Nature Asia,  Nature News, Companion research briefing at Nature; WITF interview, 澎湃新闻)
3. Khunsriraksakul C, McGuire D, Sauteraud R, Chen F, Yang L, Wang L, …, Liu DJ. Integrating 3D genomic and epigenomic data to enhance target gene discovery and drug repurposing in transcriptome-wide association studies. Nature Communications. 2022 Jun 7;13(1):3258. (link) (Media coverage:  Penn State News and Penn State Health News).
4.  Sauteraud R, Stahl JM, James J, Englebright M, Chen F, Zhan X, Carrel L, Liu DJ. Inferring genes that escape X-Chromosome inactivation reveals important contribution of variable escape genes to sex-biased diseases. Genome research. 2021 Sep;31(9):1629-1637. (link)
5. McGuire D, Jiang Y, Liu M, Weissenkampen JD, Eckert S, Yang L, Chen F, GSCAN, Berg A, Vrieze S, Jiang B, Li Q & Liu DJ Model-based assessment of replicability for genome-wide association meta-analysis, Nature Communications (link) (media coverage: AcademicTimes, Penn State News)
6. Cygan PH, Arnold-Croop SE, Weidman EA, Chen F, Liu DJ, Eyster ME, Carrel L. Investigation of discordant phenotype in mild Hemophilia A using whole exome sequencing. Thrombosis Research. 2020 Sep 1;193:36-9. (link)
7. Cygan PH, Arnold-Croop SE, Weidman EA, Chen F, Liu DJ, Eyster ME, Carrel L. Bleeding in Mild Hemophilia A Due to a Splice-Site F8 Mutation May be Fully Abrogated By Prothrombotic Gene Variants. Blood. 2019 Nov 13;134:1125. (link)
8. Liu M, Jiang Y, Wedow R, Li Y, Brazel DM, Chen F, Datta G, …, Abecasis G, Liu DJ, Vrieze S. Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use. Nature Genetics. 2019 Feb;51(2):237-244. (link) (media coverage: GenomeWeb, NIH/NIDA, 澎湃新闻, Penn State Health News, Penn State News)
9. Cao L*, Chen F*, Yang X, Xu W, Xie J, Yu L. Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages. BMC evolutionary biology. 2014 Jan 17;14:10. (link)
10. Chen F, Li R, Wang C, Cao L, Wang Y, Yu L. T‐LAK cell‐originated protein kinase is essential for the proliferation of hepatocellular carcinoma SMMC‐7721 cells. Cell Biochemistry and Function. 2013 Dec;31(8):736-42. (link) (link)

 

Selected Awards and Talks