Postdoctoral Scholar (Statistical Genetics)
11/2016-present Penn State College of Medicine
- Statistical methods and software tools implementation to efficiently and effectively analyze large scale sequence datasets (g., GSCAN, BioVU, and UKB). Cleaned, extracted, and explored input datasets over 100 GB, including genetic variations, gene expressions, and phenotypes using Python, R, SQL, and Bash.
- Working on causal inference (Mendelian Randomization) and functional analysis; trying to investigate how to interpret results from our association analysis results. Combined multiple tools such as DEPICT, Magma, and SMR to identify and prioritize key genes and pathways.
- Collaborating with doctors in the medical center on integrating bioinformatics and family-based analysis on clinical sequencing data. Performed casual variations calling in tumor-normal pairs using whole-exome sequencing data and RNA-seq sequencing data.
- Developed and built the NGS pipelines in the lab, which includes performed the data quality control, alignment, variants calling, variants annotation, analysis pipeline on multi-omics data by using Bash, R and BWA, GATK, ANNOVAR.
Product Manager (Cell analysis and Genomics)
07/2012-10/2016 BD (Becton, Dickinson and Company), Shanghai, China
- Responsible for the Marketing of BD Genomics Platform
- Annual marketing strategy and budget planning and tactics implement
- New product introduction and launch
Research Assistant (Flow Cytometry)
09/2008-12/2011 State Key Laboratory of Genetic Engineering, Fudan University, China
- Provided effective technical and applications support to staff members on flow cytometry and cell sorting
- Performed data analysis on FCM data